Names of trainees from Jean lab are underlined.
Emma-Kate Loveday, Sandra Diederich, John Pasick, and François Jean (2014) Human microRNA-24 modulates highly pathogenic avian-origin H5N1 influenza A virus infection in A549 cells by targeting secretory pathway furin. Journal of General Virology (in press)
• http://jgv.sgmjournals.org/content/early/2014/09/18/vir.0.068585-0.abstract
Plumb AW, Patton DT, Seo JH, Loveday EK, François Jean, Ziegler SF, Abraham N (2012) Interleukin-7, but not thymic stromal lymphopoietin, plays a key role in the T cell response to influenza a virus. PLoS One 7(11):e50199. doi: 10.1371/journal.pone.0050199.
• www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0050199
Anthony Khong, Roberto Forestieri, David E. Williams, Brian O. Patrick, Andrea Olmstead, Victoria Svinti, Emily Schaeffer, François Jean, Michel Roberge, Raymond J. Andersen, and Eric Jan (2012) A Daphnane Diterpenoid isolated from Wikstroemia Polyantha induces an inflammatory response and modulates miRNA activity. PLoS ONE 7(6): e39621. doi:10.1371/journal.pone.0039621
• www.plosone.org/article/info%3AdoiF10.1371%2Fjournal.pone.0039621
C. A. Thomson, Y. Wang, L. M. Jackson, M. Olson, W. Wang, A. Liavonchanka, L. Keleta, V. Silva, S. Diederich, R. B. Jones, J. Gubbay, J. Pasick, M. Petric, François Jean, V. G. Allen, E. G. Brown, J. M. Rini and J. W. Schrader (2012) Pandemic H1N1 Influenza Infection and Vaccination in Humans Induces Cross-Protective Antibodies that Target the Hemagglutinin Stem. Front. Immun.3:87. doi: 10.3389/fimmu.2012.00087
• www.frontiersin.org/B_Cell_Biology/10.3389/fimmu.2012.00087
• http://www.ncbi.nlm.nih.gov/pubmed/22586427
Emma-Kate Loveday, Victoria Svinti, Sandra Diederich, John Pasick, and François Jean (2012) Temporal and strain-specific host microRNA molecular signatures associated with swine-origin H1N1 and avian-origin H7N7 influenza A virus infection. Journal of Virology 86:6109-6122
• [Journal of Virology: Cover image (Vol. 86, Issue 12)]
• http://www.ncbi.nlm.nih.gov/pubmed/22438559
• Striking Image: Jean Lab, Journal of Virology March 21, 2012
• http://jvi.asm.org/content/86/12.cover-expansion
![[Journal of Virology: Cover image (Vol. 86, Issue 12)]](/sites/default/files/roles/drupal_jean/JV_FC_2012.jpg){kind=link}
Andrea D. Olmstead, Wolfgang Knecht, Ina Lazarov, Surjit B. Dixit, and
François Jean. (2011) Human subtilase SKI-1/S1P is a master regulator of theHCV life cycle and a potential host cell target for developing indirect-acting antiviral agents. PLoS Pathogens 2012 Jan;8(1):e1002468. Epub 2012 Jan 5.
• http://www.nature.com/scibx/journal/v5/n6/dther_index.html
• Striking Image: Jean Lab, PLoS Pathogens January 8, 2012
• http://www.ncbi.nlm.nih.gov/pubmed/22241994
Martin, M., Condotta, S., Fenn, J., Olmstead, A., Jean, F. (2011) In-cell selectivity profiling of membrane-anchored and replicase-associated hepatitis C virus NS3-4A protease reveals a common, stringent substrate recognition profile. Biological Chemistry. 2011 Jul 13. [Epub ahead of print]
• www.ncbi.nlm.nih.gov/pubmed/21749281
• PDF document
Hoshino, A., Kowalska, D., Jean, F., Lazure, C., Lindberg, I. (2011)
Modulation of PC1/3 activity by self-interaction and substrate binding Endocrinology. 152: 1402-11.
• PMID: 21303942 [PubMed - indexed for MEDLINE]
• www.ncbi.nlm.nih.gov/pubmed/21303942
• PDF document
Condotta, S., Martin, M. M., Boutin, M., Jean, F. (2010) Detection and in-cell selectivity profiling of the full-length West-Nile virus NS2B/NS3 serine protease using membrane-anchored fluorescent substrates. Biological Chemistry. 391:549-59.
• [Biological Chemistry: Cover Illustration].
• PMID: 20302513 [PubMed - indexed for MEDLINE]
• www.ncbi.nlm.nih.gov/pubmed/20302513
• PDF document
Vandekerckhove J. (2007) Paper of the Year 2006: Awarded to Pamela Hamill. Biological Chemistry. 388: 875.
• PMID: 17696769 [PubMed - indexed for MEDLINE]
• www.ncbi.nlm.nih.gov/pubmed/17696769
• PDF document
Hamill, P., Hudson, D., Kao, R., Chow, P., Raj, M., Xu, H., Richer, M., and Jean, F. (2006) Development of a red-shifted fluorescence-based assay for SARS-coronavirus 3CL protease: Identification of a novel class of anti-SARS agents from the tropical marine sponge Axinella corrugata. Biological Chemistry. 387: 1063-74.
• [Biological Chemistry: Paper of the Year 2006]
• PMID: 16895476 [PubMed - indexed for MEDLINE]
• www.ncbi.nlm.nih.gov/pubmed/16895476
• PDF document
Martin, M., Jean, F. (2006) Single-cell resolution imaging of membrane-anchored hepatitis C virus NS3/4A protease activity. Biological Chemistry. 387: 1075-80.
• [Biological Chemistry: Cover Illustration]
• PMID: 16895477 [PubMed - indexed for MEDLINE]
• www.ncbi.nlm.nih.gov/pubmed/16895477
• PDF document
Hamill, P., Jean, F. (2005) Enzymatic characterization of membrane-associated hepatitis C Virus NS3-4A heterocomplex serine protease activity expressed in human cells. Biochemistry. 44: 6586-96
• PMID: 15850392 [PubMed - indexed for MEDLINE]
• www.ncbi.nlm.nih.gov/pubmed/15850392
• PDF document
Richer, M., Keays, C., Waterhouse, J., Minhas, J., Hashimoto, C., Jean, F. (2004) The Spn4 gene of Drosophila encodes a potent furin-directed secretory pathway serpin. Proc. Natl. Acad. Sci. U.S.A. 101: 10560-10565.
• PMID: 15247425 [PubMed - indexed for MEDLINE]
• www.ncbi.nlm.nih.gov/pubmed/15247425
• PDF document
Richer, M., Juliano, L., Hashimoto, C., and Jean, F. (2004) Serpin mechanism of hepatitis C virus NS3 protease inhibition: Induced fit as a mechanism for narrow specificity. J. Biol. Chem. 279:10222-10227.
• PMID: 14701815 [PubMed - indexed for MEDLINE]
• www.ncbi.nlm.nih.gov/pubmed/14701815
• PDF document